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Sulbutiamine information from DrugsUpdate  

See Available Brands of Sulbutiamine in India

Sulbutiamine, a synthetic derivative of thiamine (vitamin B1), is prescribed for the treatment of asthenia including post-infective asthenia, psychological stress, post-partum asthenia, intellectual asthenia and emotional disorders. Sulbutiamine is also used to improve memory.

Pharmacodynamics

The exact mechanism of action of anti-asthenic drug is still unknown. However, research community believes Sulbutiamine increase physical resistance to weakness, augments learning, memory and neuromuscular efficiency. Sulbutiamine improves the metabolism of the cerebral cortex.

Pharmacokinetics

After oral administration, Sulbutiamine is rapidly absorbed in the GIT. After GI absorption, Sulbutiamine is well-distributed in all tissues. Sulbutiamine can blood-brain barrier. The half-life of Sulbutiamine is about 5 hours.

Sulbutiamine Indications / Sulbutiamine Uses

No information available

Sulbutiamine Adverse Reactions / Sulbutiamine Side Effects

Sulbutiamine can cause serious allergic skin reactions and mild agitation and behavioural changes in geriatric patients.

Precautions

Sulbutiamine is contraindicated in individuals with an allergy to synthetic vitamin supplements/minerals.

Special Precautions

No information available

Other Drug Interactions

No information available

Other Interactions

No information available

Dosage

Adults:
Consider administration of 400 mg of Sulbutiamine daily.
Geriatrics:
Consider administration of 200 mg of Sulbutiamine daily.
For severe asthenic syndrome:
Start with an initial dose of 600-800 mg as either single or divided doses.

Food(before/after)

Sulbutiamine should be taken with food

List of Contraindications

Sulbutiamine and Pregnancy

USFDA Pregnancy Category is unknown. However, Sulbutiamine should not be taken by pregnant women unless prescribed by a physician.

Sulbutiamine and Lactation

Nursing mother should consult a physician before taking Sulbutiamine

Sulbutiamine and Children

No information available

Sulbutiamine and Geriatic

No information available

Sulbutiamine and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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