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Ferrous Ascorbate+Folic Acid information from DrugsUpdate  

See Available Brands of Ferrous Ascorbate+Folic Acid in India

Ferrous Ascorbate & Folic Acid, a synthetic form of iron and vitamin C is prescribed for pregnant women to prevent spina bifida in an unborn fetus, to improve iron utilization and to prevent folate or iron deficiency anemia.

Pharmacodynamics

Ferrous ascorbate is a synthetic form of iron and vitamin C. Iron is recycled by the body and produce erythroid precursor cells. Exogenous administration of folic acid is essential for normal erythropoiesis process. Folic acid is vital for the biosynthesis of purines and thymidylate of nucleic acids. Defective purine biosynthesis due to folate deficiency leads to megaloblastic anemia and macrocytic anemia.

Pharmacokinetics

Ferrous Ascorbate:

After oral administration, the iron is predominantly absorbed in the upper jejunum and duodenum. About 90% of the administered dose is bound to plasma proteins. The iron as ferrous forms binds with transferrin and transported to the spleen, liver and bone marrow. The GI absorption of iron is very low due to systemic recycling of iron. About 1 mg/day of endogenous iron is eliminated in the urine, skin and feces.

Folic acid:

Folic acid is rapidly absorbed in the proximal portion of the small intestine. After oral administration, the Cmax can be achieved within one hour. As tetrahydrofolic acid derivative, folic acid is well-distributed in all over the body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and tetrahydrofolate forms. About 90% of the administered dose is excreted via the urine.

Ferrous Ascorbate+Folic Acid Indications / Ferrous Ascorbate+Folic Acid Uses

No information available

Ferrous Ascorbate+Folic Acid Adverse Reactions / Ferrous Ascorbate+Folic Acid Side Effects

No information available

Precautions

Ferrous ascorbate+Folic acid is contraindicated in patients with iron supplements allergy, patients with hemosiderosis, haemolytic anemia, active infections and hemochromatosis.

Special Precautions

No information available

Other Drug Interactions

Ferrous ascorbate+Folic acid may interact with barbiturates, diphenylhydantoin, primidone, tetracycline group of drugs, quinolones, penicillamine, L-dopa, methyldopa, bisphosphonates and calcium salts. 

Other Interactions

No information available

Dosage

No information available

Food(before/after)

Ferrous ascorbate+Folic acid can be taken before or after food intake

List of Contraindications

Ferrous Ascorbate+Folic Acid and Pregnancy

If taken as recommended doses, Ferrous ascorbate + Folic acid is likely safe during pregnancy.

Ferrous Ascorbate+Folic Acid and Lactation

Ferrous ascorbate + Folic acid are likely safe in lactating mothers, in recommended doses.

Ferrous Ascorbate+Folic Acid and Children

The dosage and duration should be as prescribed by a pediatrician

Ferrous Ascorbate+Folic Acid and Geriatic

No information available

Ferrous Ascorbate+Folic Acid and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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