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Valethamate information from DrugsUpdate  

See Available Brands of Valethamate in India

P - Caution when used during pregnancy

Information Not Available

Pharmacodynamics

Pharmacokinetics

A quaternary ammonium anticholinergic with peripheral actions close to those of atropine.

Valethamate Indications / Valethamate Uses

Information Not Available

Valethamate Adverse Reactions / Valethamate Side Effects

Dry mouth, blurring of vision, difficulty in swallowing and talking, constipation, urinary retention, mydriasis, arrhythmias.

Precautions

Information Not Available

Special Precautions

May impair ability to drive or operate machinery at high doses.

Other Drug Interactions

Increased antimuscarinic side effects with drugs with antimuscarinic properties e.g. amantadine, antihistamines, phenothiazide antipsychotics, TCAs. Antagonise GI effects of domperidone, metoclopramide. Delayed gastric emptying reduces absorption of other drugs.

Other Interactions

Information Not Available

Dosage

Oral
Dysmenorrhoea
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.


Oral
Postoperative pain
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.


Oral
Visceral spasms
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.

Oral
Gastrointestinal tract spasm
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.

Oral
Tenesmus
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.

Oral
Urinary tract and bile stone colic
Adult: Each tablet contains 10 mg valethamate bromide and 325 mg paracetamol. 1 tablet tid.

Parenteral
Dysmenorrhoea
Adult: 8-16 mg daily, via IM or IV inj.

Parenteral
Visceral spasms
Adult: 8-16 mg daily, via IM or IV inj.

Parenteral
Gastrointestinal tract spasm
Adult: 8-16 mg daily, via IM or IV inj.

Parenteral
Urinary tract and bile stone colic
Adult: 8-16 mg daily, via IM or IV inj.

Food(before/after)

Information Not Available

List of Contraindications

Valethamate and Pregnancy

Caution when used during pregnancy.

Valethamate and Lactation

Information Not Available

Valethamate and Children

Information Not Available

Valethamate and Geriatic

Information Not Available

Valethamate and Other Contraindications

Narrow angle glaucoma, benign prostatic hyperplasia, paralytic ileus, pyloric stenosis, ulcerative colitis, megacolon, tachyarrhythmia. Severe hepatic and renal impairment.

Storage


Oral
Store below 25°C.

Parenteral

Store below 25°C.

Lab interference


Oral
Store below 25°C.

Parenteral

Store below 25°C.

Valethamate brands in India:

Epidosin Osdil Valosin

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