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Carbocisteine information from DrugsUpdate  

See Available Brands of Carbocisteine in India

Carbocisteine, a mucolytic drug, is prescribed for the reduction of mucus in airway passages, in COPD and chronic productive cough patients. Carbocisteine can reduce the amount of mucus and reduce the stickiness of the phlegm.

Pharmacodynamics

Carbocisteine exerts mucolytic activity in the mucus membrane.

Pharmacokinetics

Carbocisteine is rapidly absorbed in the GIT. After absorption, the drug is well distributed into the pulmonary tissues and respiratory mucus membranes. The drug is mostly excreted in the urine as drug metabolites and as unchanged drug.

Carbocisteine Indications / Carbocisteine Uses

No information available

Carbocisteine Adverse Reactions / Carbocisteine Side Effects

Carbocisteine can cause skin rashes, nausea, abdominal discomfort and peptic ulcer.

Precautions

Carbocisteine should be avoided in patients with history or active peptic ulcers, patients with allergy to Carbocisteine and children less than two years of age.

Special Precautions

No information available

Other Drug Interactions

No information available

Other Interactions

No information available

Dosage

As a mucolytic (Adults):
Consider oral administration of 750 mg of Carbocisteine thrice daily. The maintenance dose should be 1.5 g in divided doses.
As a mucolytic (Pediatrics):
For children, 2-5 years of age, consider administration of 62.5-125 mg four times a day. For children, 6-12 years of age, consider administration of 250 mg of Carbocisteine thrice daily.

Food(before/after)

Carbocisteine should be taken with food

List of Contraindications

Carbocisteine and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult a healthcare provider if you are in gestation or planning to have a baby during Carbocisteine treatment. The safety of Carbocisteine is not adequately studied. However, Carbocisteine should be avoided during pregnancy.

Carbocisteine and Lactation

It is not known whether Carbocisteine pass through the breast milk or not. To avoid adverse events, do not take Carbocisteine while nursing a baby.

Carbocisteine and Children

No information available

Carbocisteine and Geriatic

No information available

Carbocisteine and Other Contraindications

No information available

Storage

Store below 25oC

Lab interference

Store below 25oC

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