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Balofloxacin information from DrugsUpdate  

See Available Brands of Balofloxacin in India

Balofloxacin, a quinolone derivative, is prescribed for the treatment of various bacterial infections including uncomplicated urinary tract infections, infective ophthalmitis, community-acquired pneumonia, acute exacerbation, sinusitis, skin infections and chronic bronchitis. Balofloxacin is effective and Gram-negative and Gram-positive microbes including MRSA and Streptococcus pneumoniae.

Pharmacodynamics

Balofloxacin exerts bactericidal property by inhibition of bacterial DNA gyrase. The enzyme is important for synthesis of bacterial DNA.

Pharmacokinetics

After oral administration, Balofloxacin is well-absorbed and distributed. The Vss of Balofloxacin is about 38 L. The drug is not primarily metabolized by hepatic enzymes. The terminal half-life of Balofloxacin is about 7-8 hours.

Balofloxacin Indications / Balofloxacin Uses

No information available

Balofloxacin Adverse Reactions / Balofloxacin Side Effects

Balofloxacin can cause moderate to severe forms of skin rashes, peripheral neuropathy and super-infections with fungal species, headache, abdominal pain, photosensitivity, nausea, esophagitis, dizziness, fever and GI upset.

Precautions

Balofloxacin is contraindicated in patients with quinolone derivatives allergy, heart problems, renal failure, jaundice and diabetes mellitus.

Special Precautions

No information available

Other Drug Interactions

Balofloxacin can interact with NSAIDs, other quinolone derivatives, theophylline and antacids containing aluminium and magnesium salts.

Other Interactions

No information available

Dosage

For infections (Adults):
Consider administration of 100 mg of Balofloxacin, twice daily.

Food(before/after)

Balofloxacin can be taken before or after food intake

List of Contraindications

Balofloxacin and Pregnancy

No information available about USFDA pregnancy category. Balofloxacin is generally contraindicated in pregnancy.

Balofloxacin and Lactation

Nursing mothers should consult a physician before taking Balofloxacin

Balofloxacin and Children

No information available

Balofloxacin and Geriatic

No information available

Balofloxacin and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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