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Varenicline information from DrugsUpdate  

See Available Brands of Varenicline in India

Varenicline is prescribed as a smoking cessation drug in cigarette smokers. Varenicline is also prescribed with behavioural changes, lifestyle modifications and counselling support to quit smoking.

Pharmacodynamics

No information available

Pharmacokinetics

No information available

Varenicline Indications / Varenicline Uses

No information available

Varenicline Adverse Reactions / Varenicline Side Effects

Do not use Varenicline, if symptoms of mood or behavioural changes including confusion, panic attacks, hallucination, maniacs, aggression, restlessness, hyperactivity, impulsivity, suicidal thoughts, self-hurting behaviours develop. Some of the other reported adverse events of Varenicline are mild rashes, shortness of breath, chest pain, light-headedness, easy bruising, nausea, weakness, insomnia, headache, dry mouth, taste changes and fatigue.

Precautions

Varenicline is contraindicated in patients with history of mental illness, renal diseases, circulatory and heart problems. Do not self-medicate drugs to quit smoking while using Varenicline. Abrupt stopping of smoking may cause behavioural and mood changes and impair thinking/cognition. Do not drive vehicle or operate heavy machineries while taking Varenicline.

Special Precautions

No information available

Other Drug Interactions

Varenicline may interact with anti-asthmatic drugs including theophylline, insulin and blood thinners like warfarin.

Other Interactions

No information available

Dosage

For Smoking Cessation (Adults):
At day 1-3, start with 0.5 mg oral dose of Varenicline, once daily. From 4-7, consider administration of 0.5 mg oral dose, twice daily. From days 8 to the end of course, consider taking 1 mg oral dose, twice daily.

Food(before/after)

No specific information

List of Contraindications

Varenicline and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult a physician if you are in gestation or planning to have a baby during Varenicline treatment.

Varenicline and Lactation

It is not known whether Varenicline can pass through the breast milk or not. Breastfeeding mothers should avoid nursing while taking Varenicline.

Varenicline and Children

Varenicline is contraindicated in children younger than 18 years of age

Varenicline and Geriatic

No specific information

Varenicline and Other Contraindications

No specific information

Storage

Store Varenicline only at room temperature, and away from moisture and heat

Lab interference

Store Varenicline only at room temperature, and away from moisture and heat

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