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Sitagliptin information from DrugsUpdate  

See Available Brands of Sitagliptin in India

Sitagliptin phosphate, an oral anti-diabetic drug, is prescribed for the treatment and management of type-2 diabetes mellitus in adults. The drug is either prescribed as a monotherapy or as a combined therapy with other anti-diabetic drugs. Sitagliptin phosphate lowers plasma glucose levels and regulates blood glucose and insulin levels. However, Sitagliptin phosphate is not indicated for type-1 diabetic patients.

Pharmacodynamics

No information available

Pharmacokinetics

No information available

Sitagliptin Indications / Sitagliptin Uses

No information available

Sitagliptin Adverse Reactions / Sitagliptin Side Effects

Sitagliptin phosphate can cause serious pancreatitis, changes in urination, severe skin reaction, runny nose, sore throat, headache, nausea, diarrhoea or constipation, myalgia, arthralgia and paced heart beats.

Precautions

Sitagliptin phosphate is contraindicated in patients with clinical history of pancreatitis and in dialysis-dependent renal patients.

Special Precautions

No information available

Other Drug Interactions

Sitagliptin phosphate may interact with insulin, oral anti-diabetic drugs, Probenecid, NSAIDs, aspirin, blood thinners, sulfa drugs, MAOIs and beta-blockers.

Other Interactions

No information available

Dosage

For Diabetes Type 2 (Adults):
Consider oral administration of 100 mg of Sitagliptin phosphate, once daily

Food(before/after)

Sitagliptin phosphate can be taken before or after food intake

List of Contraindications

Sitagliptin and Pregnancy

USFDA pregnancy category B. Sitagliptin phosphate may not cause harm to an unborn foetus. Before Sitagliptin phosphate treatment, the patient should discuss with the physician, if they are planning for a pregnancy.

Sitagliptin and Lactation

It is unclear whether the drug could pass through the breast milk to a breast feeding a baby. Consult your physician before taking Sitagliptin phosphate, if you are nursing mother.

Sitagliptin and Children

Sitagliptin phosphate should not be given to children younger than 18 years old without a Paediatrician’s advice.

Sitagliptin and Geriatic

No specific information

Sitagliptin and Other Contraindications

No specific information

Storage

Store at 20-25°C.

Lab interference

Store at 20-25°C.

Sitagliptin brands in India:

Istamet Istavel Janumet Januvia Sitar-M

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