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Pegfilgrastim information from DrugsUpdate  

See Available Brands of Pegfilgrastim in India

Pegfilgrastim, a synthetic protein, is used to prevent neutropenia due to chemotherapy. The protein stimulates synthesis of white blood cells in the bone marrow, and prevents infections.

Pharmacodynamics

No information available

Pharmacokinetics

No information available

Pegfilgrastim Indications / Pegfilgrastim Uses

No information available

Pegfilgrastim Adverse Reactions / Pegfilgrastim Side Effects

Pegfilgrastim can cause bruising and pain at the injection site, rapid breathing, infections, anorexia, vomiting, dizziness, acute abdominal pain, nausea, epistaxis, pain in the extremities, bone pain and shallow breathing.

Precautions

Pegfilgrastim is contraindicated in patients with chronic myeloid leukemia, sickle cell disorders, myelodysplastic disorders and latex-allergy.

Special Precautions

No information available

Other Drug Interactions

No information available

Other Interactions

No information available

Dosage

For Neutropenia Associated with Chemotherapy (Adults):
Consider administration of 6 mg (SC) once per chemotherapy cycle. The dose should be given at least 24 to 72 hours after course completion of chemotherapy.
 
For Neutropenia Associated with Chemotherapy (Pediatric):
For children 1 to 12 years of age, start with 100 mcg/kg once per chemotherapy cycle. The dose should be given at least 24 to 72 hours after course completion of chemotherapy. The maximum dose should not exceed 6 mg.
For children 13 to 18 years of age and over 45 kg of body weight, start with 6 mg/kg once per chemotherapy cycle. The dose should be given at least 24 to 72 hours after course completion of chemotherapy.

Food(before/after)

Information not available

List of Contraindications

Pegfilgrastim and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby during Pegfilgrastim treatment.

Pegfilgrastim and Lactation

Nursing mothers should consult the healthcare provider before Halobetasol topical treatment.

Pegfilgrastim and Children

No information available

Pegfilgrastim and Geriatic

No information available

Pegfilgrastim and Other Contraindications

No information available

Storage

Store at 20-25°C.

Lab interference

Store at 20-25°C.

Pegfilgrastim brands in India:

Imupeg Peg-Grafeel Pegex Pegstim

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