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Papaverine information from DrugsUpdate  

See Available Brands of Papaverine in India

Papaverine, a vasodilator, is prescribed for the treatment of intestinal and urine tract spasms. Papaverine relaxes blood vessels and facilitates blood flow in the spasmodic smooth muscles.

Pharmacodynamics

Papaverine exerts direct action on smooth muscles and cardiac muscles and alleviates spasms. However, the drug action is unrelated to muscle innervation. Anti-spasmodic activity of Papaverine relaxes smooth muscles of the pulmonary, coronary and systemic peripheries. Papaverine can lower cerebral vascular resistance and augments cerebral and cardiac hemodynamics.

Pharmacokinetics

No information available

Papaverine Indications / Papaverine Uses

No information available

Papaverine Adverse Reactions / Papaverine Side Effects

Discontinue Papaverine and consult a physician if symptoms of jaundice develop. Some of the other adverse events of Papaverine are arrhythmia, sweating, dizziness, anorexia, constipation, rashes, headache and flushing.

Precautions

Papaverine is contraindicated in patients with Parkinsonism, glaucoma, heart diseases and hepatic diseases. Do not operate heavy machinery or drive vehicles while taking Papaverine. Avoid getting up fast from bed after sleep to avoid falling.

Special Precautions

Information not available

Other Drug Interactions

Papaverine should not be concomitantly with Levodopa and other similar drugs.

Other Interactions

Do not consume alcohol while taking Papaverine. It may cause serious adverse events.

Dosage

Consider administration one capsule every 12 hours. In drug-unresponsive cases, the dose can be increased to one capsule every eight hours or two capsules every 12 hours.

Food(before/after)

Information not available

List of Contraindications

Papaverine and Pregnancy

FDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby.

Papaverine and Lactation

Nursing mothers should consult the healthcare provider before Papaverine treatment.

Papaverine and Children

Information not available

Papaverine and Geriatic

Information not available

Papaverine and Other Contraindications

Information not available

Storage

Store at 20-25°C.

Lab interference

Store at 20-25°C.

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